This project contains materials for "Model management and result reproducibility" training at Managing Big Data tutorial on 5th of December 2016 in Potsdam.
The course will also explain how to build an effective Data Management strategy, needed if you apply for funds for a project.
The target group of this basic course are young scientists. This one day tutorial will give you insights in standard operation procedures (SOPs), experimental design, modelling design and a short introduction in SEEK.
Programme: This Project is not associated with a Programme
The proteins cdc2 and cyclin form a heterodimer (maturation promoting factor) that controls the major events of the cell cycle. A mathematical model for the interactions of cdc2 and cyclin is constructed. … Simulation and analysis of the model show that the control system can operate in three modes: as a steady state with high maturation promoting factor activity, as a spontaneous oscillator, or as an excitable switch. We associate the steady state with metaphase arrest in unfertilized eggs, the spontaneous oscillations with rapid division cycles in early embryos, and the excitable switch with growth-controlled division cycles typical of nonembryonic cells.