Abstract (Expand)

The torrent of data emerging from the application of new technologies to functional genomics and systems biology can no longer be contained within the traditional modes of data sharing and publication ...

Authors: Katy Wolstencroft, Smedley Damian,Swertz Morris A,Proctor Glenn,Zouberakis Michael,Bard Jonathan,Hancock John M,Schofield Paul

Date Published: 30th Dec 2008

Journal: Brief. Bioinformatics

Abstract (Expand)

It is increasingly common to combine Microarray and Quantitative Trait Loci data to aid the search for candidate genes responsible for phenotypic variation. Workflows provide a means of systematically ...

Authors: Katy Wolstencroft, Fisher Paul,Hedeler Cornelia,Hulme Helen,Noyes Harry,Kemp Stephen,Stevens Robert,Brass Andrew

Date Published: 20th Aug 2007

Journal: Nucleic Acids Res.

Abstract (Expand)

BACKGROUND: During the lifetime of a fermenter culture, the soil bacterium S. coelicolor undergoes a major metabolic switch from exponential growth to antibiotic production. We have studied gene ...

Author: Nieselt Kay,Battke Florian,Herbig Alexander,Bruheim Per,Wentzel Alexander,Jakobsen Øyvind M,Sletta Håvard,Alam Mohammad T,Merlo Maria E,Lastname Firstname,Lastname Firstname,Morrissey Edward R,Juarez-Hermosillo Miguel A,Rodríguez-García Antonio,Nentwich Merle,Thomas Louise,Iqbal Mudassar,Legaie Roxane,Gaze William H,Challis Gregory L,Jansen Ritsert C,Dijkhuizen Lubbert,Rand David A,Wild David L,Bonin Michael,Reuther Jens,Wohlleben Wolfgang,Smith Margaret C M,Burroughs Nigel J,Martín Juan F,Hodgson David A,Takano Eriko,Breitling Rainer,Ellingsen Trond E,Wellington Elizabeth M H

Date Published: 28th May 2009

Journal: BMC Genomics

Abstract (Expand)

SUMMARY: Systems Biology Markup Language (SBML) is the leading exchange format for mathematical models in Systems Biology. Semantic annotations link model elements with external knowledge via unique ...

Author: Lastname Firstname,Uhlendorf Jannis,Lubitz Timo,Schulz Marvin,Klipp Edda,Liebermeister Wolfram

Date Published: 17th Nov 2009

Journal: Bioinformatics

Abstract (Expand)

This paper briefly describes the SABIO-RK database model for the storage of reaction kinetics information and the guidelines followed within the SABIO-RK project to annotate the kinetic data. Such ...

Authors: Olga Krebs, Lastname Firstname,Golebiewski Martin,Kania Renate,Mir Saqib,Weidemann Andreas,Wittig Ulrike

Date Published: 14th Sep 2007

Journal: In Silico Biol. (Gedrukt)

Abstract (Expand)

This paper examines whether the in vivo behavior of yeast glycolysis can be understood in terms of the in vitro kinetic properties of the constituent enzymes. In nongrowing, anaerobic, compressed ...

Authors: Jacky Snoep, Lastname Firstname,Passarge J,Reijenga C A,Esgalhado E,van der Weijden C C,Schepper M,Walsh M C,Bakker B M,van Dam K,Westerhoff H V

Date Published: 22nd Aug 2000

Journal: Eur. J. Biochem.

Abstract (Expand)

Taverna is an application that eases the use and integration of the growing number of molecular biology tools and databases available on the web, especially web services. It allows bioinformaticians ...

Authors: Katy Wolstencroft, Hull Duncan,Stevens Robert,Lastname Firstname,Pocock Mathew R,Li Peter,Oinn Tom

Date Published: 18th Jul 2006

Journal: Nucleic Acids Res.

Abstract (Expand)

The involvement of nicotinamide adenine nucleotides (NAD(+), NADH) in the regulation of glycolysis in Lactococcus lactis was investigated by using (13)C and (31)P NMR to monitor in vivo the kinetics ...

Author: Neves Ana Rute,Ventura Rita,Mansour Nahla,Shearman Claire,Gasson Michael J,Maycock Christopher,Ramos Ana,Santos Helena

Date Published: 13th May 2002

Journal: J. Biol. Chem.

Abstract (Expand)

Glycerol, a major by-product of ethanol fermentation by Saccharomyces cerevisiae, is of significant importance to the wine, beer, and ethanol production industries. To gain a clearer understanding of ...

Author: Cronwright Garth R,Rohwer Johann M,Prior Bernard A

Date Published: 30th Aug 2002

Journal: Appl. Environ. Microbiol.


Not specified

Author: Teif Vladimir B,Rippe Karsten

Date Published: 1st Aug 2011

Journal: Phys. Biol.

Abstract (Expand)

The use of computational modeling to describe and analyze biological systems is at the heart of systems biology. Model structures, simulation descriptions and numerical results can be encoded in ...

Author: Courtot Mélanie,Juty Nick,Knüpfer Christian,Waltemath Dagmar,Zhukova Anna,Dräger Andreas,Dumontier Michel,Finney Andrew,Golebiewski Martin,Hastings Janna,Hoops Stefan,Keating Sarah,Kell Douglas B,Kerrien Samuel,Lawson James,Lister Allyson,Lu James,Machne Rainer,Mendes Pedro,Pocock Matthew,Rodriguez Nicolas,Villeger Alice,Wilkinson Darren J,Wimalaratne Sarala,Laibe Camille,Hucka Michael,Le Novère Nicolas

Date Published: 27th Oct 2011

Journal: Mol. Syst. Biol.

Abstract (Expand)

15 untrained women were subjected to a walking treadmill test to determine the influence of maximal exercise upon synthesis of erythrocyte 2,3 DPG. Although there was a 9.8% increase in the 2,3 DPG ...

Author: Bonner H W,Tate C A,Buffington C K

Date Published: 5th Dec 1975

Journal: Eur J Appl Physiol Occup Physiol

Abstract (Expand)

The African annual fish Nothobranchius furzeri has over recent years been established as a model species for ageing-related studies. This is mainly based on its exceptionally short lifespan and the ...

Author: Petzold Andreas,Reichwald Kathrin,Groth Marco,Taudien Stefan,Hartmann Nils,Priebe Steffen,Shagin Dmitry,Englert Christoph,Platzer Matthias

Date Published: 16th Mar 2013

Journal: BMC Genomics

Abstract (Expand)

BACKGROUND: The bacterial communities of the nasopharynx play an important role in upper respiratory tract infections (URTIs). Our study represents the first survey of the nasopharynx during a known, ...

Author: Allen E. K.,Lastname Firstname,Hendley J. O.,Turner S. D.,Winther B.,Sale M. M.

Date Published: 25th Jun 2014

Journal: Microbiome


Not specified

Author: Abeyruwan Saminda,Vempati Uma D,Küçük-McGinty Hande,Visser Ubbo,Koleti Amar,Mir Ahsan,Sakurai Kunie,Chung Caty,Bittker Joshua A,Clemons Paul A,Brudz Steve,Siripala Anosha,Morales Arturo J,Romacker Martin,Twomey David,Bureeva Svetlana,Lemmon Vance,Schürer Stephan C

Date Published: 2014

Journal: J Biomed Sem

Abstract (Expand)

Four enzymes of the gluconeogenic pathway in Sulfolobus solfataricus were purified and kinetically characterized. The enzymes were reconstituted in vitro to quantify the contribution of temperature ...

Authors: Jacky Snoep, Kouril T.,Esser D.,Kort J.,Westerhoff H. V.,Siebers B.

Date Published: 22nd Aug 2013

Journal: FEBS J

Abstract (Expand)

There is an urgent need to improve the infrastructure supporting the reuse of scholarly data. A diverse set of stakeholders-representing academia, industry, funding agencies, and scholarly publishers-have ...

Author: Wilkinson M. D.,Dumontier M.,Aalbersberg I. J.,Appleton G.,Axton M.,Baak A.,Blomberg N.,Boiten J. W.,da Silva Santos L. B.,Bourne P. E.,Bouwman J.,Brookes A. J.,Clark T.,Crosas M.,Dillo I.,Dumon O.,Edmunds S.,Evelo C. T.,Finkers R.,Gonzalez-Beltran A.,Gray A. J.,Groth P.,Goble C.,Grethe J. S.,Heringa J.,'t Hoen P. A.,Hooft R.,Kuhn T.,Kok R.,Kok J.,Lusher S. J.,Martone M. E.,Mons A.,Packer A. L.,Persson B.,Rocca-Serra P.,Roos M.,van Schaik R.,Sansone S. A.,Schultes E.,Sengstag T.,Slater T.,Strawn G.,Swertz M. A.,Thompson M.,van der Lei J.,van Mulligen E.,Velterop J.,Waagmeester A.,Wittenburg P.,Wolstencroft K.,Zhao J.,Mons B.

Date Published: 16th Mar 2016

Journal: Sci Data

Abstract (Expand)

The proteins cdc2 and cyclin form a heterodimer (maturation promoting factor) that controls the major events of the cell cycle. A mathematical model for the interactions of cdc2 and cyclin is constructed. ...

Author: Tyson J. J.

Date Published: 15th Aug 1991

Journal: Proc Natl Acad Sci U S A

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